@article{ref1,
title="Does adjunctive hemoadsorption provide benefit in the management of ischemia-reperfusion syndrome following near-drowning? A case report",
journal="Frontiers in medicine",
year="2024",
author="Kovacevic, Pedja and Dragic, Sasa and Jandric, Milka and Momcicevic, Danica and Malesevic, Vedrana and Kovacevic, Tijana and Matejic-Spasic, Marijana and Knezevic, Tanja and Zlojutro, Biljana",
volume="11",
number="",
pages="e1341156-e1341156",
abstract="Drowning remains a significant global health concern, claiming over 300,000 lives annually, with a disproportionate impact on young individuals in low-and middle-income countries. Conventional mechanical ventilation, while common, falls short in addressing the hypoxemia and hypercapnia often observed in severe near-drowning cases. Veno-venous extracorporeal membrane oxygenation (vvECMO) emerges as a critical intervention for cardiopulmonary failure post-drowning. This case report delves into the pivotal role of ischemia-reperfusion injury (IRI) in a near-drowning-related pathology. Following the initial insult, reoxygenation exacerbates the inflammatory cascade, resulting in a surge of pro-inflammatory mediators. In this context, CytoSorb(®), a hemoadsorption cartridge, demonstrates promise by effectively removing these mediators from circulation. This report outlines its application in a critically ill adolescent patient who experienced near-drowning, presenting a compelling case for CytoSorb as an adjunctive therapy in managing IRI-induced hyperinflammation.<p /> <p>Language: en</p>",
language="en",
issn="2296-858X",
doi="10.3389/fmed.2024.1341156",
url="http://dx.doi.org/10.3389/fmed.2024.1341156"
}