@article{ref1,
title="Massive noninflammatory periportal liver necrosis following concentrated acetic acid ingestion",
journal="Archives of pathology and laboratory medicine",
year="2000",
author="Kamijo, Y. and Soma, K. and Iwabuchi, K. and Ohwada, T.",
volume="124",
number="1",
pages="127-129",
abstract="In a fatal occurrence of massive liver necrosis following ingestion of concentrated (90%) acetic acid, the patient showed evidence of hemolysis, disseminated intravascular coagulation, and liver dysfunction at only 45 minutes after exposure. With refractory to vigorous supportive care, the patient s condition deteriorated until death occurred 39 hours after ingestion, despite some improvement of coagulopathy. Autopsy revealed corrosive injuries in the upper gastrointestinal tract and massive hepatic necrosis in a periportal distribution without significant inflammation. A direct effect of the noxious agent on hepatocytes involving the portal circulation is suggested.<p /> <p>Language: en</p>",
language="en",
issn="0003-9985",
doi="10.5858/2000-124-0127-MNPLNF",
url="http://dx.doi.org/10.5858/2000-124-0127-MNPLNF"
}