@article{ref1,
title="Serious psychiatric disorders in an elderly population analysis of the databank of the french pharmacovigilance system over 2 years",
journal="Therapie",
year="1998",
author="Ferracin, C. and Guy, C. and Beyens, M.N. and Ratrema, M. and Ollagnier, M.",
volume="53",
number="4",
pages="e172-e172",
abstract="For 1995 and 1996, 245 cases were selected on the following criteria: admission to hospital, sequelae, vital prognosis, death, age: over 74 years old, psychiatric disorders.. The 245 cases corresponded to 86 men and 159 women. The patient's average age was 82 years. The more frequent adverse effects reported were: mental derangement (52,6 %) and clinical signs that can evoke this disease: anorexia 12,2 %, hallucination 11,4 %, restlessness 10,6 %, drowsiness 10,6 %, confusion 9,7 %, delirium 4,4 %, amnesia 2,4 %. Three attempted suicides were pointed out. The outcome was favourable for 72 % of the cases, was unknown for 20 % of the cases. There was 4,4 % of death; half of them possibly resulted from the adverse effects; 3,2 % of patients kept sequelaes. Among suspected medications, the most common classes found were cardiovascular drugs 40 %, antidepressants 22,8 %, antipsychotics 15,5 %, tacrine 11,5 %, vasodilatators and anti-ischemics 11%, minor tranquilisers 9,7 %, and hypnosedatives 8,1 %. There were 11,4 % of overdosages, most of which was associated to digitalis (7,3 %). With regard to imputability, 72 % of drugs had been imputed Ii (doubtful), 20,7 % had been imputed li (plausible), and 7,2 % had been imputed Ij (probable).<p /><p>Language: en</p>",
language="en",
issn="0040-5957",
doi="",
url="http://dx.doi.org/"
}