@article{ref1,
title="Synthesis of the suicide substrate D-propargylglycine stereospecifically labelled with deuterium and investigation of its oxidation by D-amino acid oxidase",
journal="Journal of the Chemical Society - Perkin Transactions 1",
year="1998",
author="Church, N.J. and Young, D.W.",
volume="",
number="9",
pages="1475-1482",
abstract="Stereospecifically deuteriated samples of D-propargylglycine 1 have been prepared by reaction of the labelled Pmc-protected aziridine free acids 22 with a lithium acetylide followed by deprotection. These samples have been used to show that D-amino acid oxidase, in converting D-propargylglycine to the lactone 5, deprotonates C-3 in a non-stereospecific manner. This strongly supports the idea that non-enzymic deprotonation is a key step in the formation of this compound.<p /><p>Language: en</p>",
language="en",
issn="0300-922X",
doi="10.1039/a800579f",
url="http://dx.doi.org/10.1039/a800579f"
}