@article{ref1,
title="Predictors of time to relapse/recurrence after electroconvulsive therapy in patients with major depressive disorder: A population-based cohort study",
journal="Depression research and treatment",
year="2011",
author="Nordenskjöld, A. and von Knorring, L. and Engström, I.",
volume="2011",
number="",
pages="-",
abstract="OBJECTIVE. The aim of the study is to define predictors of relapse/recurrence after electroconvulsive therapy, ECT, for patients with major depressive disorder. <br><br>METHODS. A study of all patients (n=486) treated by means of ECT for major depressive disorder was performed. The data were derived from a regional quality register in Sweden. Psychiatric hospitalisation or suicide was used as a marker for relapse/recurrence. <br><br>RESULTS. The relapse/recurrence rate within one year after ECT was 34%. Factors associated with increased risk of relapse/recurrence included comorbid substance dependence and treatment with benzodiazepines or antipsychotics during the follow-up period. <br><br>CONCLUSIONS. Within the first years after ECT, relapses/recurrences leading to hospitalisation or suicide are common. Treatment with lithium might be beneficial, while benzodiazepines, antipsychotics, or continuation ECT does not seem to significantly reduce the risk of relapse/recurrence. © 2011 Axel Nordenskjöld et al.<p /><p>Language: en</p>",
language="en",
issn="2090-1321",
doi="10.1155/2011/470985",
url="http://dx.doi.org/10.1155/2011/470985"
}