@article{ref1,
title="Treatment of bipolar depression",
journal="Medical journal of Australia",
year="2012",
author="Berk, M. and Berk, L. and Davey, C.G. and Moylan, S. and Giorlando, F. and Singh, A.B. and Kalra, H. and Dodd, S. and Malhi, G.S.",
volume="1",
number="",
pages="32-35",
abstract="Depression is usually the predominant phase in bipolar disorder, causes the most psychosocial disability, and carries significant risk of suicide.; The management of bipolar depression is relatively under-studied and poses significant challenges for clinicians.; There is substantial dissent regarding optimal pharmacotherapy for bipolar depression, particularly around the role of antidepressants.; Individual and combination pharmacotherapy should be integrated into a personalised psychosocial and lifestyle package of interventions that considers the person's clinical profile and preferences.; The relative lack of evidence relating to optimal strategies, especially when bipolar depression occurs with common comorbidities, poses challenges and requires further research.; A flexible approach and evidence-based combinations of treatments can provide effective strategies for improving quality of life and reducing morbidity and mortality. © 2012, Australasian Medical Publishing Co. Ltd. All rights reserved.<p /><p>Language: en</p>",
language="en",
issn="0025-729X",
doi="10.5694/mjao12.10611",
url="http://dx.doi.org/10.5694/mjao12.10611"
}