
@article{ref1,
title="Life-threatening bradyarrhythmia with oral phenytoin overdose",
journal="Journal of pharmacology and pharmacotherapeutics",
year="2015",
author="Srinivasan, G. and Wyawahare, M. and Mathen, P.G. and Subrahmanyam, D.K.",
volume="6",
number="3",
pages="179-181",
abstract="We report a case of a 41-year-old lady, who developed severe hypotension and sinus bradycardia, following oral consumption of 20 g of phenytoin and 500 mg of glibenclamide. She required high dose of inotropes and a temporary transvenous pacer for her hemodynamic instability. This life-threatening cardiotoxicity of phenytoin could have been due to its interaction with sulphonylurea. It is imperative to be aware of drug interactions, due to which, life-threatening cardiovascular manifestations following phenytoin toxicity can occur.<p /><p>Language: en</p>",
language="en",
issn="0976-500X",
doi="10.4103/0976-500X.162017",
url="http://dx.doi.org/10.4103/0976-500X.162017"
}