@article{ref1,
title="Correlation between violence and thyroid hormones in patients with mood disorders",
journal="Medical Journal of Wuhan University",
year="2021",
author="Xiao, Y. and li, D. and Li, Y.",
volume="42",
number="3",
pages="434-440",
abstract="OBJECTIVE: To explore the correlation between the occurrence of violent behaviors and thyroid hormones in patient with mood disorders. <br><br>METHODS: The clinical data of 182 cases of mood disorders were collected to analyze the relationship of the serum levels of FT3, FT4, and TSH to the occurrence of violence behaviors. <br><br>RESULTS: There were differences in manic episodes (χ2=40.393, P< 0.001) and depressive episodes (χ2=13.549, P< 0.001), FT3 levels (Mann-Whitney U=2 022.0, P< 0.05) and FT4 levels (Mann-Whitney U=1 992.0, P< 0.05) between the group of violence and the group of non-violence. There were differences in serum FT3 levels (Mann-Whitney U=104.0, P< 0.05) and TSH levels (Mann-Whitney U=135.0, P< 0.05) between the violence group and the non-violence group in male patients, while the differences were found in serum FT4 levels in female patients (Mann-Whitney U=975.5, P< 0.05). There were differences in serum FT3 levels (Mann-Whitney U=1 138.0, P< 0.05) and FT4 levels (Mann-Whitney U=1 214.5, P< 0.05) between the group of violence and the group of non-violence in the non-suicide patients; There were differences in serum TSH levels (Mann-Whitney U=565.0, P< 0.05) between the group of violence and the group of non-violence in the group of mania; There were differences in serum FT4 levels (Mann-Whitney U=525.5, P< 0.05) between the group of violence and the group of non-violence in the group of depression; There were differences in serum FT3 levels(Mann-Whitney U=328.5, P< 0.05) between the group of violence and the group of non-violence in the group of non-depression; Manic episodes(OR=18.109, P< 0.001), FT3 (OR=3.036, P< 0.05) and FT4 (OR=13.436, P< 0.05) were risk factors for violence behaviors in patients with mood disorders; Depressive episodes were a protective factor for violent behaviors in patients with mood disorders (OR=0.260, P< 0.001); Manic episodes (OR=23.538, P< 0.05), FT3(OR=77.577, P< 0.05) and TSH (OR=77.577, P< 0.05) were risk factors for violent behaviors in patients with mood disorders in males; Manic episodes (OR=16.162, P< 0.001) and FT4 (OR=12.663, P< 0.05) were risk factors for violent behaviors in patients with mood disorders in females; Depressive episode was a protective factor for violent behaviors in patients with mood disorders in females(OR=0.206, P< 0.05); Multivariate binary logistic regression analysis showed that FT3 (OR=870 236.339, P< 0.05) was a risk factor for violence in males. <br><br>CONCLUSION: There were differences in serum thyroid hormone levels between the violence group and the non-violence group in patients with mood disorders; Elevated serum free thyroxin level was a risk factor for violent behavior in patients with mood disorders. FT3 was a risk factor for violent behavior in male patients. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.<p /><p>Language: zh</p>",
language="zh",
issn="1671-8852",
doi="10.14188/j.1671-8852.2020.6009",
url="http://dx.doi.org/10.14188/j.1671-8852.2020.6009"
}