@article{ref1,
title="Symptom continuum reported by affective disorder patients through a structure-validated questionnaire",
journal="BMC psychiatry",
year="2020",
author="Guo, Fanjia and Cai, Jingyi and Jia, Yanli and Wang, Jiawei and Jakšić, Nenad and Kövi, Zsuzsanna and Sagud, Marina and Wang, Wei",
volume="20",
number="1",
pages="e207-e207",
abstract="BACKGROUND: Affective disorders, such as major depressive (MDD), bipolar I (BD I) and II (BD II) disorders, are overlapped at a continuum, but their exact loci are not clear. The self-reports from patients with affective disorders might help to clarify this issue. METHODS: We invited 738 healthy volunteers, 207 individuals with BD I, 265 BD II, and 192 MDD to answer a 79 item-MATRIX about on-going affective states. RESULTS: In study 1, all 1402 participants were divided random-evenly and gender-balanced into two subsamples; one subsample was used for exploratory factor analysis, and another for confirmatory factor analysis. A structure-validated inventory with six domains of Overactivation, Psychomotor Acceleration, Distraction/ Impulsivity, Hopelessness, Retardation, and Suicide Tendency, was developed. In study 2, among the four groups, MDD scored the highest on Retardation, Hopelessness and Suicide Tendency, whereas BD I on Distraction/ Impulsivity and Overactivation. CONCLUSION: Our patients confirmed the affective continuum from Suicide Tendency to Overactivation, and described the different loci of MDD, BD I and BD II on this continuum.<p /><p>Language: en</p>",
language="en",
issn="1471-244X",
doi="10.1186/s12888-020-02631-y",
url="http://dx.doi.org/10.1186/s12888-020-02631-y"
}