
@article{ref1,
title="Naloxone as an antidote for benzodiazepine: an experimental and clinical study",
journal="Egyptian journal of psychiatry",
year="1992",
author="Sanaa S., Salem and Ibrahim A., Ramadan",
volume="15",
number="1",
pages="53-65",
abstract="This study evaluates the potential antidote action of naloxone on experimentally induced diazepam and flunitrazepam [benzodiazepines] intoxication in dogs. Its antidote effects is also evaluated in a clinical sample of 8 patients suffering from flunitrazepam intoxication. The clinical findings were suggestive of an antagonistic action of naloxone in flunitrazepam intoxication. It was also found that flunitrazepam exhibits a different pharmacological profile from other members of the benzodiazepine group. Our findings of a selective naloxane-flunitrazepam reversal need to be explained in relation to the mechanism of action of this benzodiazepine, as well as to the equated naloxane-opiates reversal<p /><p>Language: en</p>",
language="en",
issn="0254-136X",
doi="",
url="http://dx.doi.org/"
}