@article{ref1,
title="Acute dystonia caused by tetrabenazine - What does it tell us about pathophysiology?",
journal="European journal of neurology",
year="1996",
author="Dietrichs, E. and Magnusson, A. and Opjordsmoen, S.",
volume="3",
number="4",
pages="395-396",
abstract="A 21-year-old woman with Gilles de la Tourette syndrome developed acute dystonia 24 h after ingesting 750 mg of tetrabenazine in a suicide attempt. The symptoms were rapidly resolved on diazepam and orphenadrine administration. Acute dystonia caused by tetrabenazine is extremely rare, but may help us understand the pathophysiology of drug-induced dystonic reactions. We suggest that acute dystonia in this patient was caused by catecholamine depletion and a subsequently reduced dopaminergic neurotransmission rather than by dopamine receptor blockade.<p /><p>Language: en</p>",
language="en",
issn="1351-5101",
doi="10.1111/j.1468-1331.1996.tb00236.x",
url="http://dx.doi.org/10.1111/j.1468-1331.1996.tb00236.x"
}