@article{ref1,
title="Use of granulocyte colony-stimulating factor in the treatment of pancytopenia secondary to colchicine overdose",
journal="Annals of pharmacotherapy",
year="1992",
author="Katz, R. and Chuang, L. C. and Sutton, J. D.",
volume="26",
number="9",
pages="1087-1088",
abstract="OBJECTIVE: To report a case of pancytopenia following colchicine overdose and to discuss the use of granulocyte colony-stimulating factor (G-CSF) for treating this severe complication. CASE SUMMARY: A 19-year-old man developed pancytopenia four days after ingestion of approximately 50-60 0.6-mg colchicine tablets in a suicide attempt. His pancytopenia resolved after subcutaneous administration of one 300-micrograms dose of G-CSF. The patient recovered from his other multiorgan disturbances during his hospitalization and was discharged from the hospital with elevated liver enzyme concentrations. CONCLUSIONS: Colchicine overdose is rare, but can be fatal. The use of G-CSF appears to be beneficial in alleviating bone marrow depression in colchicine overdose situations.<p /><p>Language: en</p>",
language="en",
issn="1060-0280",
doi="10.1177/106002809202600907",
url="http://dx.doi.org/10.1177/106002809202600907"
}