
@article{ref1,
title="Clozapine cases with fatal, toxic or therapeutic concentrations",
journal="International journal of legal medicine",
year="1993",
author="Worm, K. and Kringsholm, B. and Steentoft, A.",
volume="106",
number="3",
pages="115-118",
abstract="The neuroleptic drug clozapine is used in the treatment of schizophrenia and is characterized by not having the extrapyramidal side-effects usually shown by neuroleptics. Unfortunately clozapine has other side-effects, which limit its use. This study presents methods for the analysis of clozapine and desmethylclozapine in whole blood and tissue. Case histories and pathology findings are described for 3 autopsy cases with fatal concentrations of clozapine, 5 with toxic concentrations and 2 with therapeutic concentrations together with the concentrations found in a living person.<p /><p>Language: en</p>",
language="en",
issn="0937-9827",
doi="10.1007/BF01225229",
url="http://dx.doi.org/10.1007/BF01225229"
}