
@article{ref1,
title="Thioridazine enantiomers in human tissues",
journal="Forensic science international",
year="1994",
author="Jortani, S. A. and Valentour, J. C. and Poklis, A.",
volume="64",
number="2-3",
pages="165-170",
abstract="Enantiomers of thioridazine (TRZ) were determined in postmortem tissues obtained from a patient on chronic TRZ therapy by sequential achiral and chiral high pressure liquid chromatography. Tissue concentrations of (+)-TRZ found in liver, brain, bile and blood were: 6.46, 0.40, 0.48 and 0.07 mg/l or mg/kg, respectively. Concentrations of (-)-TRZ in liver, brain, bile and blood were: 12.2, 0.81, 1.07 and 0.20 mg/l or mg/kg, respectively. These data demonstrate the stereoselective disposition of TRZ in human tissues.<p /><p>Language: en</p>",
language="en",
issn="0379-0738",
doi="10.1016/0379-0738(94)90227-5",
url="http://dx.doi.org/10.1016/0379-0738(94)90227-5"
}