@article{ref1,
title="Serotonin and suicidality: the impact of fluoxetine administration. II: Acute neurobiological effects",
journal="Israel journal of psychiatry and related sciences",
year="1995",
author="Anderson, G. M. and Segman, R. H. and King, R. A.",
volume="32",
number="1",
pages="44-50",
abstract="Despite the demonstrated anti-depressant efficacy of the selective serotonin reuptake inhibitors (SSRIs), increased suicidal ideation and/or agitation have been reported in a small proportion of individuals receiving fluoxetine or other SSRIs. Part II of this review examines fluoxetine's acute effects on serotonergic functioning. Although acute fluoxetine administration produces a short-term compensatory decrease in the firing of 5-HT neurons, the neurobiological data reviewed suggests that this decrease probably does not lead to an over-compensatory net decrease in 5-HT functioning. The implications of fluoxetine's complex effects on the 5-HT systems are discussed with respect to clinical practices and future research.<p /><p>Language: en</p>",
language="en",
issn="0333-7308",
doi="",
url="http://dx.doi.org/"
}