@article{ref1,
title="Naloxone reversal of hypotension due to captopril overdose",
journal="Annals of emergency medicine",
year="1991",
author="Varon, J. and Duncan, S. R.",
volume="20",
number="10",
pages="1125-1127",
abstract="The hemodynamic effects of captopril and other angiotensin-converting enzyme inhibitors may be mediated by the endogenous opioid system. The opioid antagonist naloxone has been shown to block or reverse the hypotensive actions of captopril. We report a case of an intentional captopril overdose, manifested by marked hypotension, that resolved promptly with the administration of naloxone. To our knowledge, this is the first reported case of captopril-induced hypotension treated with naloxone. Our experience demonstrates a possible role of naloxone in the reversal of hypotension resulting from captopril.<p /><p>Language: en</p>",
language="en",
issn="0196-0644",
doi="10.1016/s0196-0644(05)81389-7",
url="http://dx.doi.org/10.1016/s0196-0644(05)81389-7"
}