@article{ref1,
title="[The effect of neostigmine on the motor endplate in the intermediate syndrome of organophosphate poisoning]",
journal="EEG-EMG Zeitschrift fur Elektroenzephalographie - Elektromyographie und verwandte Gebiete",
year="1991",
author="Besser, R.",
volume="22",
number="1",
pages="37-39",
abstract="A patient with severe organophosphate intoxication received Neostigmine 1 mg IV during the intermediate syndrome. This dose resulted clinically and neurophysiologically in a marked deterioration of neuro-muscular transmission. This effect of neostigmine on the neuromuscular block during the intermediate syndrome (deterioration) differs from its effect on a similar pattern (improvement), which is seen in the delayed neuropathy following organophosphate exposure. The administration of therapeutic doses of cholinesterase inhibitors in patients with a reduced safety margin due to inhibition of endplate acetylcholinesterase may be dangerous.<p /><p>Language: de</p>",
language="de",
issn="0012-7590",
doi="",
url="http://dx.doi.org/"
}