
@article{ref1,
title="β-fluoro-substituted aminoacids",
journal="Russian Chemical Reviews",
year="1990",
author="Kukhar, V.P. and Yagupolskii, Y.L. and Soloshonok, V.A.",
volume="59",
number="1",
pages="89-102",
abstract="The review gives a systematic account of data concerning the methods of synthesis of α-, β-, and γ-aminoacids containing fluorine atoms in the β-position relative to the aminogroup. The interest in these compounds is in many respects due to the fact that most of them have proved to be hijghly selective irreversible inhibitors of pyridoxal-5-phosphate-dependent enzymes acting via the &quot;suicide-substrate&quot; mechanism. Attention is concentrated on β-fluoro-derivatives of natural α -aminoacids. © 1990 The Chemical Society.<p /><p>Language: en</p>",
language="en",
issn="0036-021X",
doi="10.1070/RC1990v059n01ABEH003512",
url="http://dx.doi.org/10.1070/RC1990v059n01ABEH003512"
}