@article{ref1,
title="Characterization of major depression symptoms in multiple sclerosis patients",
journal="Journal of neuropsychiatry and clinical neurosciences",
year="1996",
author="Scott, T. F. and Allen, D. and Price, T. R. and McConnell, H. and Lang, D.",
volume="8",
number="3",
pages="318-323",
abstract="Retrospective review of affective disturbances in 238 patients with multiple sclerosis (MS) seen over a 6-month period revealed: 1) 51 patients (22%) received pharmacologic treatment for depressive symptoms during or within 4 years of the study period, and 17 (7%) received treatment for rapid mood swings; 2) among the 51 depressed patients, response rate to medication was extremely high; 3) relapse of depressive symptomatology after discontinuation of medication was also high (17/29); 4) first episodes of major depression frequently occurred during periods of MS progression or exacerbation, but first episodes also occurred during periods of relative clinical stability; 5) suicidal ideation was common (12 patients), but only 1 patient had a history of attempted suicide; and 6) side effects were tolerable in most patients.<p /><p>Language: en</p>",
language="en",
issn="0895-0172",
doi="10.1176/jnp.8.3.318",
url="http://dx.doi.org/10.1176/jnp.8.3.318"
}