@article{ref1,
title="Evaluation of endozepine-like immunoreactivity in the frontal cortex of suicide victims",
journal="Neuroreport",
year="1998",
author="Rochet, T. and Tonon, M. C. and Kopp, N. and Vaudry, H. and Miachon, S.",
volume="9",
number="1",
pages="53-56",
abstract="Diazepam-binding inhibitor (DBI) and its processing products, including the octadecaneuropeptide (ODN), are polypeptides called endozepines which have multiple biological effects, including regulation of mitochondrial steroidogenesis and modulation of GABA-gated chloride channels. Concentrations of ODN-like immunoreactivity (ODN-Li) were measured by radioimmunoassay in the frontal cortex of nine drug-free suicides and nine drug-free sudden-death victims. The level of ODN-Li was higher in the right than in the left frontal cortex, in both suicide (p < 0.05) and control (p < 0.02) subjects. No significant differences were found between suicides and controls either in the right and left cortex, or when considering the gender and the post-mortem diagnosis of depression.<p /><p>Language: en</p>",
language="en",
issn="0959-4965",
doi="10.1097/00001756-199801050-00011",
url="http://dx.doi.org/10.1097/00001756-199801050-00011"
}