@article{ref1,
title="Simultaneous determination of cyanide and thiocyanate in blood by ion chromatography with fluorescence and ultraviolet detection",
journal="Journal of chromatography. B, biomedical sciences and applications",
year="1998",
author="Chinaka, S. and Takayama, N. and Michigami, Y. and Ueda, K.",
volume="713",
number="2",
pages="353-359",
abstract="An ion chromatographic method for the simultaneous determination of cyanide and thiocyanate in blood has been developed. After extraction by adding water and methanol to blood, cyanide was derivatized with 2,3-naphthalenedialdehyde and taurine to give a fluorescent product of 1-cyanobenz[f]isoindole. This compound was detected with high sensitivity by fluorometry and the underivatized thiocyanate was detected by ultraviolet absorption. The detection limits were 3.8 pmol ml(-1) for cyanide and 86 pmol ml(-1) for thiocyanate, and the recoveries from blood were ca. 83% and ca. 100%, respectively. The proposed method was successfully applied to the analysis of both anions in blood from smokers, non-smokers and fire victims.<p /><p>Language: en</p>",
language="en",
issn="1387-2273",
doi="10.1016/s0378-4347(98)00176-5",
url="http://dx.doi.org/10.1016/s0378-4347(98)00176-5"
}