@article{ref1,
title="Depression does not influence basal ganglia-mediated psychomotor speed in HIV-1 infection",
journal="Journal of neuropsychiatry and clinical neurosciences",
year="2001",
author="von Giesen, H. J. and Backer, R. and Hefter, H. and Arendt, G.",
volume="13",
number="1",
pages="88-94",
abstract="The authors examined the effects of depressive mood (Hamilton Rating Scale for Depression [Ham-D]) on basal ganglia-mediated psychomotor speed (motor test battery) in 202 HIV-1 seropositive homosexual males with no prior history of antiretroviral treatment. HIV-1 seropositive patients showed a significant slowing of most rapid alternating movements (MRAM) and significantly prolonged contraction times (CT) compared with 66 HIV-1 seronegative male control subjects. Factor analysis of Ham-D scores isolated a factor containing the items depressed mood, suicide, and psychic and somatic anxiety. This factor did not correlate with MRAM or CT. Depression and psychomotor speed are independent in HIV-1infection.<p /><p>Language: en</p>",
language="en",
issn="0895-0172",
doi="10.1176/jnp.13.1.88",
url="http://dx.doi.org/10.1176/jnp.13.1.88"
}