@article{ref1,
title="[Episodes of depression with attempted suicide after taking valsartan with hydrochlorothiazide]",
journal="Deutsche Medizinische Wochenschrift",
year="2003",
author="Ullrich, H. and Passenberg, P. and Agelink, M. W.",
volume="128",
number="48",
pages="2534-2536",
abstract="HISTORY AND CLINICAL FINDINGS: A 43-year-old woman was admitted after a suicide attempt with 1.5 g atenolol. Physical and neurological examination showed no abnormality, but psychiatric examination revealed symptoms of a major depression. Four weeks prior to admission a valsartan-hydrochlorothiazide combination had been added to the antihypertensive medication. INVESTIGATIONS: Laboratory tests, electrocardiography, chest-x-ray, electroencephalography and cranial computerised tomography showed no abnormality. DIAGNOSIS AND COURSE: The depressive disorder resolved within ten days after discontinuation of valsartan and hydrochlorothiazide without specific treatment. Blood pressure was normal under treatment with metoprolol. CONCLUSION: Depressive drug reactions can produce a substantial morbidity. This case of a drug induced affective disorder should heighten the awareness of unusual reactions to valsartan-hydrochlorothiazide therapy.<p /><p>Language: de</p>",
language="de",
issn="0012-0472",
doi="10.1055/s-2003-44949",
url="http://dx.doi.org/10.1055/s-2003-44949"
}