@article{ref1,
title="Acute oxcarbazepine and atomoxetine overdose with quetiapine",
journal="Veterinary and human toxicology",
year="2004",
author="Barker, Michael J. and Benitez, John G. and Ternullo, Sharon and Juhl, Gregory A.",
volume="46",
number="3",
pages="130-132",
abstract="We present a case of acute oxcarbazepine and atomoxetine overdose combined with excess quetiapine in a 19-y-old male. The patient ingested approximately 36 g oxcarbazepine (514 mg/kg), 1.2 g atomoxetine (17 mg/kg), and 9 mg Quetiapine (128 mg/kg). Central nervous system (CNS) depression with initial unresponsiveness developed within 1 h of ingestion, necessitating intubation for airway protection. Despite aggressive therapy with whole bowel irrigation and charcoal administration, the patient's somnolence persisted for 4 d, punctuated by occasional violent outbursts. Prolonged QTc was noted initially, but normalized within 4 d. This case suggests that acute overdose of oxcarbazepine and atomoxetine combined with quetiapine is associated with rapid and prolonged CNS depression.<p /><p>Language: en</p>",
language="en",
issn="0145-6296",
doi="",
url="http://dx.doi.org/"
}