@article{ref1,
title="Severe mental illness in depression",
journal="Acta psychiatrica Scandinavica. Supplementum",
year="2006",
author="Moller, H.-j. and Bottlender, R.",
volume="",
number="429",
pages="64-68",
abstract="OBJECTIVE: The study aimed to evaluate the outcome from in-patient treatment in major depressive disorders (MDD) and its impact on the patients' 1 year outcome under the present routine care conditions. METHOD: The reported data stem from a multicentric follow-up study on the course and outcome of patients with MDD. Patients enrolled in the study had their first or multiple psychiatric hospitalization and fulfilled the ICD-10 criteria for a depressive disorder. During in-patient treatment patients were standardized assessed in 2-weekly intervals, with yearly follow-up evaluations after discharge. RESULTS: The analyses revealed that the elimination of depressive symptoms and a return to premorbid levels of functioning is a rarity in the in-patient treatment of MDD. Moreover, the analyses revealed that the achieved level of response during in-patient treatment clearly determines the patients state 1 year after discharge from in-patient treatment. CONCLUSION: Considering that persisting depressive symptoms are associated with a range of unfavourable outcomes, the present data point to a serious problem in the treatment of MDD and the urgent need to further optimize antidepressive treatment strategies.<p /><p>Language: en</p>",
language="en",
issn="0065-1591",
doi="10.1111/j.1600-0447.2005.00720.x",
url="http://dx.doi.org/10.1111/j.1600-0447.2005.00720.x"
}