@article{ref1,
title="Validation of remission criteria for schizophrenia",
journal="American journal of psychiatry",
year="2006",
author="van Os, Jim and Drukker, Marjan and à Campo, Joost and Meijer, Jaap and Bak, M. and Delespaul, Philippe",
volume="163",
number="11",
pages="2000-2002",
abstract="OBJECTIVE: Remission criteria for schizophrenia have been proposed, consisting of a time criterion and a symptomatic remission criterion. With longitudinal data of a representative patient group (N=317; median follow-up: 1,132 days), validity of the symptomatic remission criterion was investigated. METHOD: In a group of 145 patients meeting the symptomatic remission criterion at baseline and a group of 172 patients not meeting it at baseline, change over time in remission status was examined in relation to change in various functional outcomes. RESULTS: In both groups, change over time with the symptomatic remission criterion was associated with substantial changes in unmet needs, Global Assessment of Functioning scale scores, satisfaction with services and, to a lesser extent, quality of life. Changing the symptomatic remission criterion to include depression and suicidality did not affect the results. CONCLUSIONS: The proposed symptomatic remission criterion has clinical validity and represents the right balance between parsimony and inclusiveness.<p /><p>Language: en</p>",
language="en",
issn="0002-953X",
doi="10.1176/ajp.2006.163.11.2000",
url="http://dx.doi.org/10.1176/ajp.2006.163.11.2000"
}