@article{ref1,
title="CB2 selective sulfamoyl benzamides: optimization of the amide functionality",
journal="Bioorganic and medicinal chemistry letters",
year="2009",
author="Goodman, Allan J. and Ajello, Christopher W. and Worm, Karin and Le Bourdonnec, Bertrand and Savolainen, Markku A. and O'Hare, Heather and Cassel, Joel A. and Stabley, Gabriel J. and Dehaven, Robert N. and Labuda, Christopher J. and Koblish, Michael and Little, Patrick J. and Brogdon, Bernice L. and Smith, Steven A. and Dolle, Roland E.",
volume="19",
number="2",
pages="309-313",
abstract="Previous research within our laboratories identified sulfamoyl benzamides as novel cannabinoid receptor ligands. Optimization of the amide linkage led to the reverse amide 40. The compound exhibited robust antiallodynic activity in a rodent pain model when administered intraperitoneally. Efficacy after oral administration was observed only when ABT, a cytochrome P450 suicide inhibitor, was coadministered.<p /><p>Language: en</p>",
language="en",
issn="0960-894X",
doi="10.1016/j.bmcl.2008.11.091",
url="http://dx.doi.org/10.1016/j.bmcl.2008.11.091"
}