@article{ref1,
title="Altered glucose tolerance in women with deliberate self-harm",
journal="Psychoneuroendocrinology",
year="2009",
author="Westling, Sofie and Ahrén, Bo and Sunnqvist, Charlotta and Träskman-Bendz, Lil",
volume="34",
number="6",
pages="878-883",
abstract="Disturbances in glucose metabolism are of importance for violent behaviour in men, but studies in women are lacking. We used the 5h-oral glucose tolerance test (OGTT) in this study of 17 female psychiatric patients, selected for violent behaviour directed against themselves (deliberate self-harm) and 17 healthy controls matched for age and BMI. Following OGTT, patients had higher glucose levels at 30 min (p=0.007) and increased glucagon area under the curve (p=0.011). Since a co-morbid eating disorder might affect results, we as a post-hoc analysis subgrouped the patients and found that the increased glucagon levels only were present in patients with an eating disorder. In contrast, those without an eating disorder showed a significantly lower p-glucose nadir (p=0.015) and unaltered glucagon levels compared to controls. There were no significant differences in insulin and C-peptide levels between patients and controls. We conclude that deliberate self-harm in women may be associated with alterations in carbohydrate metabolism in certain groups. Eating disorder is a confounding factor.<p /><p>Language: en</p>",
language="en",
issn="0306-4530",
doi="10.1016/j.psyneuen.2008.12.015",
url="http://dx.doi.org/10.1016/j.psyneuen.2008.12.015"
}