@article{ref1,
title="Comorbidities of obsessive and compulsive symptoms in Huntington's disease",
journal="Journal of nervous and mental disease",
year="2010",
author="Anderson, Karen E. and Gehl, Carissa R. and Marder, Karen S. and Beglinger, Leigh J. and Paulsen, Jane S. and Huntington's Study Group, ",
volume="198",
number="5",
pages="334-338",
abstract="Although current reports document a high rate of obsessive and compulsive symptoms (O/Cs) in Huntington's disease (HD), there have been no studies published that have made an attempt to identify comorbidities of O/Cs in HD. We examined O/Cs in 1642 individuals with a diagnosis of HD. Of those endorsing significant O/Cs (27.2%), nearly one-quarter reported obtaining treatment for obsessive compulsive disorder. Individuals with HD and O/Cs were older, had poorer functioning, and a longer duration of illness than those without O/Cs. Individuals with HD and O/Cs endorsed significantly higher psychiatric comorbidities of depression, suicidal ideation, aggression, delusions, and hallucinations. Participants with the most severe O/Cs and worse performance on the Stroop task, a measure of executive function. Clinicians should be aware that patients with HD and O/Cs might have a somewhat different clinical picture from those without, and may require a specialized treatment plan.<p /><p>Language: en</p>",
language="en",
issn="0022-3018",
doi="10.1097/NMD.0b013e3181da852a",
url="http://dx.doi.org/10.1097/NMD.0b013e3181da852a"
}