@article{ref1,
title="Clozapine-withdrawal catatonia",
journal="Psychosomatics",
year="2010",
author="Wadekar, Mitali and Syed, Saba",
volume="51",
number="4",
pages="355-355.e2",
abstract="BACKGROUND: Case reports in which abrupt clozapine discontinuation led to a return of psychosis, autonomic instability, or catatonia have been previously presented in the literature. OBJECTIVE: The authors report on symptom presentation and resolution in a case of abrupt withdrawal of clozapine medication. METHOD: The authors describe the condition and history of the patient, a 49-year-old woman with schizophrenia, the medical support she received, and the re-initiation of her clozapine medication. RESULTS: Symptoms of catatonia and autonomic instability resolved by Day 4 of treatment. CONCLUSION: Patients and their caregivers need to be educated about the effects of abrupt cessation of clozapine administration.<p /><p>Language: en</p>",
language="en",
issn="0033-3182",
doi="10.1176/appi.psy.51.4.355",
url="http://dx.doi.org/10.1176/appi.psy.51.4.355"
}