@article{ref1,
title="Indirect inactivation of tyrosinase in its action on tyrosine",
journal="Acta biochimica Polonica",
year="2011",
author="Munoz-Munoz, Jose Luis and García-Molina, Francisco and Acosta-Motos, Jose Ramon and Arribas, Enrique and García-Ruiz, Pedro Antonio and Tudela, José and García-Cánovas, Francisco and Rodriguez-Lopez, Jose Neptuno",
volume="58",
number="4",
pages="477-488",
abstract="Under aerobic conditions, tyrosinase is inactivated by dopa as a result of suicide inactivation, and, under anaerobic conditions, as a result of irreversible inactivation. However, tyrosine protects the enzyme from being inactivated by dopa under anaerobic conditions. This paper describes how under aerobic conditions the enzyme acting on tyrosine is not directly inactivated but undergoes a process of indirect suicide inactivation provoked by reaction with the o-diphenol originated from the evolution of o-dopaquinone and accumulated in the reaction medium.<p /><p>Language: en</p>",
language="en",
issn="0001-527X",
doi="",
url="http://dx.doi.org/"
}