@article{ref1,
title="The impact of attention deficit hyperactivity disorder in obsessive-compulsive disorder subjects",
journal="Depression and anxiety",
year="2019",
author="Blanco-Vieira, Thiago and Santos, Matheus and Ferrão, Ygor A. and Torres, Albina R. and Miguel, Eurípedes C. and Bloch, Michael H. and Leckman, James F. and do Rosário, Maria C.",
volume="36",
number="6",
pages="533-542",
abstract="BACKGROUND: Recent findings suggest an association between attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). Thus, we evaluated the clinical associated features of ADHD in a large sample of adult OCD patients. METHODS: A cross-sectional study including 955 adult patients with OCD from the Brazilian Research Consortium of Obsessive-Compulsive Spectrum Disorders (C-TOC). Clinical characteristics in adult OCD patients with and without comorbid ADHD were compared using Fisher's exact test, t-tests or Mann-Whitney tests. Bivariate analyses were followed by logistic regression analysis to identify clinical characteristics independently associated with ADHD comorbidity. RESULTS: The lifetime prevalence of ADHD in adult OCD patients was 13.7%. The current results indicate that OCD + ADHD patients were more severe, had an earlier onset of the obsessive-compulsive symptoms, a higher history of rheumatic fever, with higher frequencies of sensory phenomena and comorbidity with Tourette syndrome. They also had an increased risk for academic impairment and suicide attempts. CONCLUSION: Adult OCD patients with ADHD present some specific clinical features and may represent a special subgroup of adult OCD. Future studies should focus on the development of interventions more tailored to the phenotype of this subgroup of patients.<p /><p>Language: en</p>",
language="en",
issn="1091-4269",
doi="10.1002/da.22898",
url="http://dx.doi.org/10.1002/da.22898"
}