@article{ref1,
title="Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report",
journal="JRSM cardiovascular disease",
year="2016",
author="Amiri, Hassan and Zamani, Nasim and Hassanian-Moghaddam, Hossein and Shadnia, Shahin",
volume="5",
number="",
pages="e2048004016682178-e2048004016682178",
abstract="Poisoning with tricyclic antidepressants is an important cause of drug-related self-poisoning in the developed world and a very common cause of poisoning and mortality in developing countries. Electrocardiographic manifestations of most tricyclic antidepressant-poisoned patients resolve by the administration of 1-2 mEq/kg of sodium bicarbonate. Some rare cases have been reported who have been resistant to the long-term or high doses of bicarbonate administration. We present a case of acute tricyclic antidepressant toxicity referring with status epilepticus, hypotension, and refractory QRS complex widening that resolved after the intravenous administration of 2650 mEq sodium bicarbonate.<p /><p>Language: en</p>",
language="en",
issn="2048-0040",
doi="10.1177/2048004016682178",
url="http://dx.doi.org/10.1177/2048004016682178"
}