@article{ref1,
title="Long-term lithium prophylaxis in recurrent unipolar depression: a controversial indication?",
journal="Acta psychiatrica Belgica",
year="1985",
author="Lepkifker, E. and Horesh, N. and Floru, S.",
volume="85",
number="3",
pages="434-443",
abstract="Assessed results obtained with long-term lithium maintenance in a group of 33 recurrent unipolar depression patients who were followed regularly for 1-15 yrs. Ss' diagnoses were confirmed in accordance with the Schedule for Affective Disorders and Schizophrenia--Life-time Version and the Diagnostic and Statistical Manual of Mental Disorders (DSM-III). For a comparison of 'before' vs 'during' lithium treatment, both the whole course of the disorder before treatment and its course during the 5-yr period immediately prior to lithium were considered. Also analyzed were changes of frequency, severity, and duration of depressive relapses; rate and duration of hospitalization; suicidal ideas or attempts; and various assessments of outcome. A significant reduction in symptoms was found on all indices during lithium management as compared to before lithium treatment, attesting to the efficacy of long-term prophylactic lithium treatment in recurrent unipolar depression. (French, Dutch, Italian & Spanish abstracts) (PsycInfo Database Record (c) 2020 APA, all rights reserved)<p />",
language="fr",
issn="0300-8967",
doi="",
url="http://dx.doi.org/"
}