@article{ref1,
title="Successful treatment for serious depression with suicidal risk in a heart transplant patient",
journal="Revista Colombiana de psiquiatría (English ed.)",
year="2024",
author="Arango-Posada, María Del Mar and Prada-Escobar, Ana Isabel and Marín-Hernández, Carolina and Monsalve-Franco, Veronica and Restrepo-Bernal, Diana",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="INTRODUCTION: Major depressive disorder is related to unfavourable outcomes in patients with severe comorbidities. In transplant patients, major depression is associated with worse clinical outcomes. CASE REPORT: We present the case of a 55-year-old man with a heart transplant due to heart failure of ischaemic origin. Six months after the transplant he developed depressed mood, anhedonia and suicidal ideation with a score of 20/27 on the PHQ-9 depression screening scale. After receiving mirtazapine 30 mg/night for a week and persisting with a high suicide risk, it was decided to administer ketamine infusion for 24 h, with which a significant improvement in mood was observed, and the disappearance of suicidal ideation 24 h after the infusion. <br><br>DISCUSSION: Depression in transplant patients is a factor associated with graft loss and post-transplant mortality, in addition to favouring other negative outcomes such as deep vein thrombosis. <br><br>CONCLUSIONS: Ketamine infusion was shown to be an effective and safe option to treat major depression with suicidal risk in a heart transplant patient.<p /> <p>Language: es</p>",
language="es",
issn="2530-3120",
doi="10.1016/j.rcpeng.2022.03.001",
url="http://dx.doi.org/10.1016/j.rcpeng.2022.03.001"
}