@article{ref1,
title="Suicidal behaviour and mortality in first-episode psychosis: the OPUS trial",
journal="British journal of psychiatry. Supplement",
year="2007",
author="Bertelsen, Mette and Jeppesen, Pia and Petersen, Lone and Thorup, Anne and Øhlenschlaeger, J and le Quach, Phuong and Christensen, Torben Ostergaard and Krarup, G. and Jørgensen, P and Nordentoft, Merete",
volume="51",
number="Suppl",
pages="s140-6",
abstract="BACKGROUND: Those with first-episode psychosis are at high-risk of suicide. AIMS: To identify predictive factors for suicidal thoughts, plans and attempts, and to investigate the rate of suicides and other deaths during the 5 years after first diagnosis and initiation of treatment. METHOD: A longitudinal, prospective, 5-year follow-up study of 547 individuals with first-episode schizophrenia spectrum psychosis. Individuals presenting for their first treatment in mental health services in two circumscribed urban areas in Denmark were included in a randomised controlled trial of integrated v. standard treatment. All participants were followed in the Danish Cause of Death Register for 5 years. Suicidal behaviour and clinical and social status were assessed using validated interviews and rating scales at entry, and at 1- and 2-year follow-ups. RESULTS: Sixteen participants died during the follow-up. We found a strong association between suicidal thoughts, plans and previous attempts, depressive and psychotic symptoms and young age, and with suicidal plans and attempts at 1- and 2-year follow-up. CONCLUSIONS: In this first-episode cohort depressive and psychotic symptoms, especially hallucinations, predicted suicidal plans and attempts, and persistent suicidal behaviour and ideation were associated with high risk of attempted suicide.<p /> <p>Language: en</p>",
language="en",
issn="0960-5371",
doi="10.1192/bjp.191.51.s140",
url="http://dx.doi.org/10.1192/bjp.191.51.s140"
}