@article{ref1,
title="A Cohort Study of Pesticide Poisoning and Depression in Colorado Farm Residents",
journal="Annals of epidemiology",
year="2008",
author="Beseler, Cheryl L. and Stallones, Lorann",
volume="18",
number="10",
pages="768-774",
abstract="PURPOSE: Depressive symptoms have been associated with pesticide poisoning among farmers in cross-sectional studies, but no longitudinal studies have assessed the long-term influence of poisoning on depressive symptoms. The purpose of this study was to describe the associations between pesticide poisoning and depressive symptoms in a cohort of farm residents. METHODS: Farm operators and their spouses were recruited in 1993 from farm truck registrations using stratified probability sampling. The Center for Epidemiologic Studies-Depression scale was used to evaluate depression in participants using generalized estimating equations. Baseline self-reported pesticide poisoning was the exposure of interest in longitudinal analyses. RESULTS: Pesticide poisoning was significantly associated with depression in three years of follow-up after adjusting for age, gender, and marital status (odds ratio [OR] 2.59; 95% confidence interval [CI] 1.20-5.58). Depression remained elevated after adjusting for health, decreased income, and increased debt (OR 2.00; CI 0.91-4.39) and was primarily due to significant associations with the symptoms being bothered by things (OR 3.29; CI 1.95-5.55) and feeling everything was an effort (OR 1.93; CI 1.14-3.27). CONCLUSIONS: Feeling bothered and that everything was an effort were persistently associated with a history of pesticide poisoning, supportive of the hypothesis that prolonged irritability may result from pesticide poisoning.  <p></p>  <p>Language: en</p>",
language="en",
issn="1047-2797",
doi="10.1016/j.annepidem.2008.05.004",
url="http://dx.doi.org/10.1016/j.annepidem.2008.05.004"
}