@article{ref1, title="Efficacy and safety of paediatric medicinal cannabis use: a scoping review", journal="Paediatrics and child health (1996)", year="2021", author="Pawliuk, Colleen and Chau, Briana and Rassekh, S. Rod and McKellar, Terri and Siden, Harold Hal", volume="26", number="4", pages="228-233", abstract="INTRODUCTION: The use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety.

OBJECTIVE: To map the available evidence on the efficacy and safety of medicinal cannabis in children and adolescents.

METHODS: We conducted a scoping review and searched six electronic databases and grey literature. A study was eligible for inclusion when it investigated the efficacy or safety of medicinal cannabis for any condition, more than half of the participants were 0 to 18 years old, and had any study design except single case reports.

RESULTS: We included 36 studies in our final analysis, 32 of which investigated the efficacy or safety of cannabis in treatment-resistant epilepsy. The remaining 4 studies examined patients with cancer, dysautonomia, Epidermolysis Bullosa, and motor disorders.

CONCLUSIONS: There is a lack of evidence on the efficacy and safety of medicinal cannabis in most paediatric conditions.

Language: en

", language="en", issn="1205-7088", doi="10.1093/pch/pxaa031", url="http://dx.doi.org/10.1093/pch/pxaa031" }