%0 Journal Article
%T Methadone- and buprenorphine-related ambulance attendances: a population-based indicator of adverse events
%J Journal of substance abuse treatment
%D 2008
%A Nielsen, Suzanne
%A Dietze, Paul
%A Cantwell, Kate
%A Lee, N.
%A Taylor, Diana
%V 35
%N 4
%P 457-461
%X This study examined the nature and extent of methadone- and buprenorphine-related morbidity through a retrospective analysis of ambulance service records (N = 243) in Melbourne, Australia. Cases in which methadone and buprenorphine were implicated are examined. Demographic and presenting characteristics, transport outcomes, and other substance use were explored. There were 84 buprenorphine-related attendances and 159 methadone-related attendances recorded on the database over the 4-year period. Presenting signs (respiratory rate and Glasgow Coma Scale score) were lower in the methadone-related attendances. Most of the attendances resulted in transport to hospital. Most presentations did not involve traditional signs of opioid overdose, a finding that warrants further investigation. This is the first article to describe characteristics of methadone- and buprenorphine-related ambulance attendances, with results suggesting this may be a useful way to monitor harms associated with these medications in the future.<p /> <p>Language: en</p>
%G en
%I Elsevier Publishing
%@ 0740-5472
%U http://dx.doi.org/10.1016/j.jsat.2007.12.007