%0 Journal Article
%T Nonsteroidal anti-inflammatory drugs and coma: a case report of fenoprofen overdose
%J Annals of emergency medicine
%D 1990
%A Kolodzik, J. M.
%A Eilers, M. A.
%A Angelos, M. G.
%V 19
%N 4
%P 378-381
%X We present the case of a 17-year-old girl who ingested 24 to 36 g fenoprofen as a suicidal gesture. She presented with coma, hypotension, metabolic acidosis, and respiratory depression within four hours of ingestion. The most common adverse effects of the nonsteroidal anti-inflammatory drugs occur in both therapeutic and toxic doses and include gastrointestinal upset, blood dyscrasias, and analgesic nephropathy. The propionic acid derivatives of nonsteroidal anti-inflammatory drugs, including fenoprofen and ibuprofen, are rarely associated with severe toxic effects. This is the first report of pure fenoprofen overdose presenting as coma and metabolic acidosis.<p /><p>Language: en</p>
%G en
%I Elsevier Publishing
%@ 0196-0644
%U http://dx.doi.org/