%0 Journal Article
%T Does clozapine promote employability and reduce offending among mentally disordered offenders?
%J Canadian journal of psychiatry, The
%D 2010
%A Balbuena, Lloyd
%A Mela, Mansfield
%A Wong, Stephen
%A Gu, Deqiang
%A Adelugba, Olajide O.
%A Tempier, Raymond
%V 55
%N 1
%P 50-56
%X OBJECTIVE: To compare employment pay, count of infractions, and clinical symptoms in psychiatric inmates treated with clozapine or other antipsychotics after 6 months of treatment. <br><br>METHODS: Clinical charts and institutional offence records of psychiatric inmates (n = 98), comprised of those on clozapine (n = 65) and on other antipsychotics (n = 33), were reviewed at baseline and after 6 months of treatment. The outcome measures used were Brief Psychiatric Rating Scale (BPRS) scores, employment pay, medication compliance, and the frequency of institutional offences. A binary logistic regression model was used to analyze a categorical change in pay variable, while a negative binomial model was used to analyze the frequency of infractions. <br><br>RESULTS: Treatment with clozapine was associated with greater odds of a pay increase (OR = 3.13; 95% CI 1.3 to 7.53, P = 0.01). However, patients on other antipsychotics had a more favourable improvement in BPRS (F = 5.44, df = 1,57, P = 0.02). Patients on other antipsychotics also had a higher count of posttreatment offences (Incidence Rate Ratio = 2.22; 95% CI 1.11 to 4.41, P = 0.02). <br><br>CONCLUSION: Clozapine probably has a favourable effect on inmate behaviour and institutional adjustment. This effect can last up to 36 months after the initial dose.<p /><p>Language: en</p>
%G en
%I SAGE Publications
%@ 0706-7437
%U http://dx.doi.org/