%0 Journal Article
%T Y chromosome STR typing in crime casework
%J Forensic science, medicine, and pathology
%D 2009
%A Roewer, Lutz
%V 5
%N 2
%P 77-84
%X Since the beginning of the nineties the field of forensic Y chromosome analysis has been successfully developed to become commonplace in laboratories working in crime casework all over the world. The ability to identify male-specific DNA renders highly variable Y-chromosomal polymorphisms, the STR sequences, an invaluable addition to the standard panel of autosomal loci used in forensic genetics. The male-specificity makes the Y chromosome especially useful in cases of male/female cell admixture, namely in sexual assault cases. On the other hand, the haploidy and patrilineal inheritance complicates the interpretation of a Y-STR match, because male relatives share for several generations an identical Y-STR profile. Since paternal relatives tend to live in the geographic and cultural territory of their ancestors, the Y chromosome analysis has a potential to make inferences on the population of origin of a given DNA profile. This review addresses the fields of application of Y chromosome haplotyping, the interpretation of results, databasing efforts and population genetics aspects.<p /><p>Language: en</p>
%G en
%I Holtzbrinck Springer Nature Publishing Group
%@ 1547-769X
%U http://dx.doi.org/10.1007/s12024-009-9089-5