%0 Journal Article
%T Relationship between fatigue after acquired brain injury and depression, injury localization and aetiology: an explorative study in a rehabilitation setting
%J Journal of rehabilitation medicine
%D 2018
%A Holmqvist, Anna
%A Lindstedt, Märta Berthold
%A Möller, Marika C.
%V 50
%N 8
%P 725-731
%X OBJECTIVE: Fatigue after acquired brain injury may be related to the subcortico-frontal attention network. Depression is also strongly related to fatigue. This study investigates whether injury localization, diagnosis and depression are related to self-rated mental fatigue in patients with an acquired brain injury. <br><br>DESIGN: Retrospective cross-sectional cohort study. SUBJECTS: Sixty-one patients diagnosed with stroke, subarachnoidal haemorrhage, traumatic brain injury, or brain tumour were included in the study. <br><br>METHODS: Patients who underwent a multidisciplinary team assessment during September 2011 to June 2012, and who were assessed with the Mental Fatigue Scale, were included in the study. <br><br>RESULTS: A significantly higher number of patients with posterior and non-specific lesions experienced fatigue compared with those with subcortical/frontal injuries. Fewer stroke patients experienced fatigue compared with the other patient groups. However, after logistic regression, only depression remained as an explanatory variable for self-rated fatigue. Nevertheless, although all patients with depression were fatigued, not all fatigued patients were depressed. <br><br>CONCLUSION: Although depression explains a high degree of fatigue after an acquired brain injury, mental fatigue after brain injury should be viewed as a condition partly separate from depression. Future extensive comparative studies are required, preferably including neuropsychological measures.<p /> <p>Language: en</p>
%G en
%I Foundation for Rehabilitation Information
%@ 1650-1977
%U http://dx.doi.org/10.2340/16501977-2365