
%0 Journal Article
%T Sociodemographic and clinical risk factors for suicidal ideation and suicide attempt in functional/dissociative seizures and epilepsy: a large cohort study
%J BMJ mental health
%D 2024
%A Faiman, Irene
%A Hodsoll, John
%A Jasani, Iman
%A Young, Allan H.
%A Shotbolt, Paul
%V 27
%N 1
%P e300957-e300957
%X BACKGROUND: People with functional/dissociative seizures (FDS) are at elevated suicidality risk. <br><br>OBJECTIVE: To identify risk factors for suicidality in FDS or epilepsy. <br><br>METHODS: Retrospective cohort study from the UK's largest tertiary mental healthcare provider, with linked national admission data from the Hospital Episode Statistics. Participants were 2383 people with a primary or secondary diagnosis of FDS or epilepsy attending between 01 January 2007 and 18 June 2021. Outcomes were a first report of suicidal ideation and a first hospital admission for suicide attempt (International Classification of Diseases, version 10: X60-X84). Demographic and clinical risk factors were assessed using multivariable bias-reduced binomial-response generalised linear models. <br><br>FINDINGS: In both groups, ethnic minorities had significantly reduced odds of hospitalisation following suicide attempt (OR: 0.45-0.49). Disorder-specific risk factors were gender, age and comorbidity profile. In FDS, both genders had similar suicidality risk; younger age was a risk factor for both outcomes (OR: 0.16-1.91). A diagnosis of depression or personality disorders was associated with higher odds of suicidal ideation (OR: 1.91-3.01). In epilepsy, females had higher odds of suicide attempt-related hospitalisation (OR: 1.64). Age had a quadratic association with both outcomes (OR: 0.88-1.06). A substance abuse disorder was associated with higher suicidal ideation (OR: 2.67). Developmental disorders lowered the risk (OR: 0.16-0.24). <br><br>CONCLUSIONS: This is the first study systematically reporting risk factors for suicidality in people with FDS. <br><br>RESULTS for the large epilepsy cohort complement previous studies and will be useful in future meta-analyses. CLINICAL IMPLICATIONS: Risk factors identified will help identify higher-risk groups in clinical settings.<p /> <p>Language: en</p>
%G en
%I BMJ Publishing Group
%@ 2755-9734
%U http://dx.doi.org/10.1136/bmjment-2023-300957