TY - JOUR PY - 2008// TI - QT Prolongation and delayed atrioventricular conduction caused by acute ingestion of trazodone JO - Clinical toxicology (Philadelphia, Pa.) A1 - Service, Jennifer A. A1 - Waring, W. S. SP - 71 EP - 73 VL - 46 IS - 1 N2 - Trazodone possesses minimal anticholinergic properties and, therefore, is generally regarded as having less cardiotoxic potential than other antidepressants. This report describes a young woman who developed significant QT prolongation and delayed atrioventricular nodal conduction after acute trazodone overdose. The case adds to the existing literature because it has a number of strengths, namely that confounding drugs and alcohol were lacking, trazodone exposure was confirmed by drug assay, and early presentation to hospital gave a valuable opportunity to study the time-course of the cardiac effects. This case reminds us to consider the possibility of cardiotoxic effects after trazodone overdose, even in young patients with no established cardiovascular disease.
Language: en
LA - en SN - 1556-3650 UR - http://dx.doi.org/10.1080/15563650701275322 ID - ref1 ER -