TY  - JOUR
PY  - 2008//
TI  - Vasopressin-neurophysin and DST in major depression: relationship with suicidal behavior
JO  - Journal of psychiatric research
A1  - Pitchot, W.
A1  - Scantamburlo, Gabrielle
A1  - Pinto, Emmanuel
A1  - Hansenne, M.
A1  - Reggers, Jean
A1  - Ansseau, M.
A1  - Legros, Jean-Jacques
SP  - 684
EP  - 688
VL  - 42
IS  - 8
N2  - The purpose of the present study was to assess if AVP-neurophysin is associated with hypercortisolemia and suicidal behaviour in depressed patients. The study included 28 patients subgrouped into suicide attempters (n=13) and nonattempters (n=15). We assessed basal AVP-neurophysins concentrations and post-dexamethasone (DST) cortisol levels. Concentrations of AVP-neurophysins did not differ between DST suppressors and nonsuppressors: 0.29+/-0.13 ng/ml vs 0.36+/-0.21 ng/ml, (F=1.1, df=1, 27, p=0.30). Suicide attempters did not differ from nonattempters for AVP-neurophysins levels. Our results fail to support a role of AVP in the early cortisol escape.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-3956
UR  - http://dx.doi.org/10.1016/j.jpsychires.2007.07.007
ID  - ref1
ER  -