TY  - JOUR
PY  - 2008//
TI  - A rare cause of abdominal compartment syndrome: acute trichlorethylene overdose
JO  - Clinical toxicology (Philadelphia, Pa.)
A1  - Liotier, Jerome
A1  - Barbier, Marie
A1  - Plantefeve, Gaetan
A1  - Duale, Christian
A1  - Deteix, Patrice
A1  - Souweine, Bertrand
A1  - Coudoré, Francois
SP  - 905
EP  - 907
VL  - 46
IS  - 9
N2  - INTRODUCTION: The clinical signs of acute trichlorethylene overdose are commonly coma, cardiac conduction disturbances, diarrhea, and vomiting. We report a case of intentional massive trichlorethylene ingestion inducing a fatal abdominal compartment syndrome (ACS). CASE REPORT: A 47-year-old woman was admitted to the emergency department after intentionally ingesting 500 mL of trichlorethylene and benzodiazepines. She rapidly developed coma and abdominal distension leading to multiple organ failure. Subsequent surgical evaluation revealed abdominal perforation and necrosis, and life-sustaining treatments were therefore withdrawn. DISCUSSION: This is a primary ACS that can be explained from experimental data on the pathophysiology of pneumatosis cystoides coli. For this case, we discuss multiple etiological factors for intra-abdominal hypertension (IAP), such as paralytic ileus and massive fluid resuscitation due to the direct toxicity of ingested trichlorethylene. CONCLUSION: Patients ingesting trichlorethylene need to be closely evaluated for risk of digestive damage and perforation. Early prompt laparotomy must be performed in cases of ACS.<p />  <p>Language: en</p>
LA  - en
SN  - 1556-3650
UR  - http://dx.doi.org/10.1080/15563650802269893
ID  - ref1
ER  -