TY  - JOUR
PY  - 2008//
TI  - Alterations of coagulation in metformin intoxication
JO  - Hormones : international journal of endocrinology and metabolism
A1  - Akinci, Baris
A1  - Yener, Serkan
A1  - Bengi, Goksel
A1  - Yesil, Sena
SP  - 325
EP  - 329
VL  - 7
IS  - 4
N2  - It is widely known that metformin reduces the levels of circulating pro-coagulant factors and improve fibrinolytic activity in type 2 diabetes when used in therapeutic doses. Potential alterations of coagulation have not been reported in patients with metformin intoxication. We evaluated certain components of the coagulation system in a patient with metformin intoxication upon admission and after recovery. Our results indicate that both the levels of coagulation proteins synthesized by the liver and the anti-coagulant activity decrease temporarily in metformin intoxication. Nevertheless, no change in the coagulation factors secreted by the endothelium were observed.<p />  <p>Language: en</p>
LA  - en
SN  - 1109-3099
UR  - http://dx.doi.org/
ID  - ref1
ER  -