TY  - JOUR
PY  - 2007//
TI  - Prospective case-control study of interictal depression and suicidal ideation in Nigerians with epilepsy
JO  - Nigerian postgraduate medical journal
A1  - Okubadejo, N. U.
A1  - Danesi, M. A.
A1  - Aina, O. F.
A1  - Ojini, F. I.
A1  - Adeyemi, J. D.
A1  - Olorunshola, D. A.
SP  - 204
EP  - 208
VL  - 14
IS  - 3
N2  - BACKGROUND: Co-morbid depression and suicidal ideation in people with epilepsy (PWE) in developing countries are under-recognised, and so may be consequently undertreated. This study was designed to determine the frequency and clinical correlates of interictal depression and suicidal ideation in PWE. PATIENTS AND METHODS: Using a prospective design, we evaluated 96 PWE and two groups of controls (103 age- and sex-matched population controls and 13 persons with DSM - IV diagnosis of major depression (controls with depression - CWD) without epilepsy. Depression was assessed using Zung Self-rating depression scale (scores =40 indicating depression). RESULTS: Depression was more prevalent in PWE (25/96 i.e. 26.0%) than normal controls (10/103 i.e. 9.7%) (P = 0.004). Suicidal ideation scores were similar for depressed PWE and depressed normal controls (1.7 +/-1.0 v. 1.5 +/- 1.0; P>0.05), but significantly higher in CWD (2.61.3; P=0.04). Among PWE, mean duration of epilepsy (years) was the only variable significantly related to depression (i.e. 12.7 8.8 in depressed PWE v. 8.3 6.6 in non-depressed PWE (P=0.01). CONCLUSION: Depressive symptomatology is a frequent co-morbidity in our tertiary care population of PWE. However, suicidal ideation is less common in contrast to persons with major depression.<p />  <p>Language: en</p>
LA  - en
SN  - 1117-1936
UR  - http://dx.doi.org/
ID  - ref1
ER  -