TY  - JOUR
PY  - 2007//
TI  - Altered processing of sensorimotor feedback in schizophrenia
JO  - Comptes Rendus Biologies
A1  - Posada, Andres
A1  - Franck, N.
A1  - Augier, Segolene
A1  - Georgieff, Nicolas
A1  - Jeannerod, M.
SP  - 382
EP  - 388
VL  - 330
IS  - 5
N2  - Schizophrenia is characterized by an altered sense of the reality, associated with hallucinations and delusions. Some theories suggest that schizophrenia is related to a deficiency of the system that generates information about the sensory consequences of the actions realized by the subject. This system monitors the reafferent information resulting from an action and allows its anticipation. In the present study, we examined visual-event-related potentials (ERPs) generated by a sensorimotor task in 15 patients with schizophrenia and 15 normal controls. The visual feedback from hand movements performed by the subjects was experimentally distorted. Behavioral results showed that patients were impaired in recognizing their own movements. The ERP signal in patients also differed from those of control subjects. In patients, the ERP waveform was affected during the early part of the response (200 ms). This early effect in schizophrenic patients reveals a modified processing of the visual consequence of their actions.<p />  <p>Language: en</p>
LA  - en
SN  - 1631-0691
UR  - http://dx.doi.org/10.1016/j.crvi.2007.02.003
ID  - ref1
ER  -